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Temporal trends in Group A Streptococcus epidemiology, antimicrobial susceptibility and emm-type distribution: a seven-year surveillance study from a UK district general hospital

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Background: Group A Streptococcus (GAS) remains universally susceptible to penicillin; however, resistance to macrolides and clindamycin varies geographically and may affect management, particularly in patients with penicillin al... ...