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Subthalamic Nucleus Deep Brain Stimulation in Early-onset Parkinson's Disease: Clinical Outcomes in LRRK2 Mutation Carriers Compared to Non-Carriers

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Introduction: Subthalamic nucleus deep brain stimulation (STN-DBS) is an established treatment for early-onset Parkinson's disease (EOPD). While the effect of STN-DBS on patients with LRRK2 G2019S mutation has been largely inves... ...