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A novel polyester-drug nanoconjugate with subtype selectivity for high efficacy against PSMA-positive prostate cancer

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Prostate-specific membrane antigen (PSMA) positive prostate cancer (PCa) accounts for 80-90% cases. Docetaxel (DTX) is a first-line chemotherapy drug for metastatic castration resistant prostate cancer (mCRPC) and has exhibited promising efficacy. However, DTX... ...