Homocysteine and S-adenosyl-L-homocysteine impair development and methylation in yeast and flies
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S-adenosyl-L-homocysteine (SAH), the product inhibitor of S-adenosyl-L-methionine-dependent methyltransferases, and its degradation product homocysteine (Hcy) are evolutionarily conserved master regulators of methylation metabolism, which is mediated by more t... ...