Discovery of a novel dual-target modulator of ULK1 and ERK1/2 that suppresses triple-negative breast cancer progression and metastasis via the Exo70/Cav-1/MMPs axis
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Triple-negative breast cancer (TNBC) represents an aggressive breast cancer subtype with unfavorable clinical outcomes. Because actionable therapeutic targets remain limited, current treatment options are suboptimal and patient prognosis is generally poor. Our... ...