Protonation of Key Acidic Residues Reveals Binding Features of PCABs to Gastric H, K-ATPase
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The group of inhibitors known as Potassium Competitive Acid Blockers (PCABs) has become one of the main topics of current research into reducing gastric H,K-ATPase activity. The design of novel PCABs relies on structure-based drug design strategies that integr... ...
