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Melatonin Alleviates Sleep Disturbance-Induced Ovarian Reserve Decline by Suppressing NLRP3-Mediated Pyroptosis in Granulosa Cells

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Sleep disturbance perturbs circadian and immune homeostasis and is increasingly associated with female reproductive dysfunction, yet the underlying cellular mechanisms remain unclear. Here, we identify granulosa cell pyroptosis as a central mechanism linking s... ...