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Uridine cytidine kinases govern molnupiravir bioactivation and anti-SARS-CoV-2 activity

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Molnupiravir is a nucleoside analogue antiviral drug against RNA viruses, including its clinical indication SARS-CoV-2. Whilst its mechanism-of-action is well defined, host factors that regulate its therapeutic responses have not been thoroughly deciphered and... ...