PRKN Ser131 phosphorylation promotes cigarette smoke-induced mitophagy impairment and epithelial cell senescence via MKK3/p38 MAPK activation: An in vitro and in vivo study
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Introduction: Cigarette smoke (CS) exposure impairs mitochondrial function and promotes senescence in airway epithelial cells, contributing to the pathogenesis of chronic obstructive pulmonary disease (COPD). However, the molecul... ...
