Design, synthesis, anticancer activity, and mechanistic investigation of 4,5,6,7-tetrahydrobenzo[ b]thiophene carboxamides as CDK-2 inhibitors: in vitro and in silico DFT and molecular docking study
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Utilising drug design methodologies including bioisosteric modification and substituents variation, sets of 4,5,6,7-tetrahydrobenzo[b]thiophene carboxamides were synthesised, by conventional heating and eco-friendly microwave-assisted techniques, as CDK-2 inhi... ...
