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New high affinity AT2 receptor ligands comprising a 2-methyl substituted phenylthiophene scaffold

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A series of 2-substituted methylene imidazolephenylthiophene and tert-butylimidazolyl acetylphenylthiophene sulfonylcarbamate and sulfonamide derivatives were synthesized and assessed as AT2R ligands. Substitution at this position of the phenyl ring, located b... ...