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Stable β2-Microglobulin-HLA Class I Association Reshapes the Antigenic Landscape and TCR Recognition of Cancer-Associated Epitopes

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β2-Microglobulin (β2m) is essential for the stability and surface expression of human leukocyte antigen class I (HLA-I) molecules. While β2m's structural role is well established, its influence on the antigenic landscape remains incompletely understood. He... ...