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Repurposing Purine Analog Antivirals to Modulate Serum Uric Acid: Evidence From Real-World Data

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Xanthine oxidase (XO) inhibitors remain the standard pharmacologic therapy for hyperuricemia. However, additional enzymatic components of the purine degradation pathway may contribute to uric acid synthesis. Guanine deaminase (GD) catalyzes the conversion of g... ...