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Stoichiometric simultaneous quantification of mycophenolate mofetil and mycophenolic acid in paired culture medium and cell extracts by common product ion LC-MS/MS

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Mycophenolate mofetil (MMF) is an immunosuppressive prodrug whose efficacy depends on conversion to mycophenolic acid (MPA). Quantitative, stoichiometry-ready measurement of MMF-to-MPA conversion in matched extracellular and intracellular matrices remains limi... ...