Discovery of Novel 5-Substituted-4-Allyl-1,2,4-Triazoles as Potential Nonsteroidal Anti-Inflammatory Agents via Downregulation of iNOS Expression
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Inducible nitric oxide synthase (iNOS) is a key mediator of inflammatory signaling, and excessive iNOS-derived nitric oxide (NO) contributes to the pathology of multiple chronic inflammatory disorders. Herein, we report the design and synthesis of a focused se... ...
