Cannabidiolic acid causes a defect in tail retraction of migrating MDA-MB-231 cells: Possible involvements of Rho-associated protein kinases (ROCKs) inhibition and accumulation of vinculin at the rear of migrating cells
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We previously reported that cannabidiolic acid (CBDA), a major cannabinoid constituent of the fiber-type cannabis plant, abrogates the migration of highly aggressive human breast cancer MDA-MB-231 cells and activates the small GTPase RhoA by inhibiting protein... ...