Matrix metalloproteinases in intestinal fibrosis and fibrostenosing Crohn's disease: Current evidence, mechanistic hypotheses, and translational challenges
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Fibrostenosing complications in Crohn's disease arise from mixed transmural remodeling that includes inflammation, fibrosis, and muscular hypertrophy/hyperplasia. Matrix metalloproteinases (MMPs) are implicated in extracellular matrix turnover and inflammator... ...
