Deciphering the role of chondroitin sulfate a in insulin fibrillation at room temperature: a biophysical and computational perspective
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Chondroitin sulfate A (CSA), a natural mucopolysaccharide of the extracellular matrix, plays a critical role in amyloidogenesis. This study explores the interaction between CSA and human insulin, with emphasis on conformational transitions and amyloid fibril f... ...
