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In vivo quantification of mitochondrial O2 affinity in human skeletal muscle using 1H-magnetic resonance spectroscopy of deoxy-myoglobin

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Mitochondrial oxygen (O2) affinity is a fundamental determinant of oxidative phosphorylation capacity, which has yet to be directly measured in human skeletal muscle in vivo. To determine the apparent mitochondrial O2 affinity (i.e. P50) of the skeletal muscle... ...