Molecular characterization and expression dynamics of Labeo rohita MDA5, its adaptor MAVS and pro-inflammatory cytokines against PAMPs stimulation and pathogen challenge
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Melanoma differentiation-associated gene 5 (MDA5) is a prime member of the RIG-I-like receptor (RLR) family that recognises viral RNA in the cytoplasm and triggers antiviral innate immunity mainly via the MAVS-dependent signalling cascade. This study reports t... ...