Aberrant Activation of Renal Functional Reserve and Reduced Tubule Flow, but not Obstruction, is Associated with Cystogenesis in Pkd2 Mutant Kidneys
{{output}}
Disruption of PKD2 function causes polycystic kidney disease (PKD) and leads to the formation of cysts in the kidney in both mice and humans. PKD is progressive, initiating with the formation of tubule dilations that expand into large cysts, causing the destru... ...
