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Twist1 overexpression models an aggressive subtype of pancreatic ductal adenocarcinoma in vivo

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Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer with poor survival outcomes. Genomic analyses have identified distinct molecular subtypes in human PDAC with the quasimesenchymal/squamous/basal-like (QSB) subtype having the worst prognosis. However, ... ...