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In-vitro evaluation of Cefiderocol and Ceftazidime/Avibactam against MDR and XDR gram-negative pathogens from clinical isolates, with whole genome sequencing-based analysis of Antimicrobial Resistance Genes in Cefiderocol-resistant Escherichia coli

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Purpose: The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-negative bacilli (GNB) poses a major therapeutic challenge. This study evaluated the in-vitro activity of cefiderocol and the synergist... ...