Histone H3K27 demethylation drives Crohn's disease inflammation: GSK-J4 as a potential epigenetic therapy
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Background: Crohn's disease (CD) is characterised by recurrent gastrointestinal inflammation. Epigenetic modifications, particularly the methylation of histone H3 at lysine 27 trimethylation (H3K27me3), are crucial in regulating... ...
