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Study on the Mechanism of Berberine Reversing MRSA Resistance to β-Lactam Antibiotics by Inhibiting blaZ Expression

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This study elucidates a novel mechanism by which the natural product berberine (BBR) reverses methicillin-resistant Staphylococcus aureus (MRSA) resistance to β-lactam antibiotics. It was established that BBR interferes with the BlaR1/BlaI regulatory pathway ... ...