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Design, synthesis and antibacterial evaluation of novel unsaturated butenolide-fatty amine hybrids against multidrug-resistant pathogens

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To address the growing public health challenge of multidrug-resistant bacterial infections, 26 new butenolide amides bearing fatty chains of different lengths (CnH2n+1, n = 4-16) were designed and synthesized and evaluated for their antibacterial activity. The... ...