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The Diving Reflex Elicits Potent, Non-Electrophilic Nrf2 Activation via Trigeminal CGRP Signaling

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Activation of nuclear factor erythroid 2-related factor 2 (Nrf2) is a powerful neuroprotective strategy, yet clinical translation to conditions of high stress remains limited by the paradoxical depletion of glutathione and increase of reactive oxygen species o... ...