Arl8b inactivates the Rab11a recycling pathway to promote LAMP1 sorting and lysosome biogenesis
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The small GTP-binding protein Arl8b is established as a regulator of lysosome positioning and fusion, yet its role in lysosome biogenesis remains unclear. Here, we investigate the role of Arl8b in the trafficking of newly synthesized LAMP1 to lysosomes using t... ...