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COL10A1 beyond skeletal development: a hypertrophic chondrocyte-specific collagen emerging as a potential biomarker and tumor microenvironment regulator in solid cancers

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Type X collagen (COL10A1) is an extracellular matrix protein primarily expressed by hypertrophic chondrocytes and is essential for endochondral ossification and skeletal mineralization. Although traditionally regarded as cartilage-specific, recent studies have... ...