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Targeting the mitochondrial thermogenesis pathway for neuroprotection in neonatal hypoxic-ischemic encephalopathy by curcumin

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Neonatal hypoxic-ischemic (HI) brain injury remains a major cause of death and long-term neuro-disability leading to hypoxic-ischemic encephalopathy (HIE), and current hypothermia therapy is only partially effective. Curcumin is a polyphenolic compound with an... ...