Cytokine and Oxylipin Production in Resting and LPS-Stimulated Monocytes From Americans of African Ancestry Are Influenced by ALOX5 Promoter Tandem Repeat Polymorphisms
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The arachidonate 5-lipoxygenase (ALOX5) specificity protein 1 (Sp1) promoter tandem repeat polymorphism is associated with enhanced cardiovascular disease (CVD) risk. However, a functional understanding of these variants in immune cells central to disease deve... ...
