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Small molecule agonists of Toll-like receptors 7 and 8: an updated patent review 2021 - 2025

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Introduction: Toll-like receptors 7 (TLR7) and 8 (TLR8) are endosomal receptors that sense single‑stranded RNA and activate MyD88‑dependent inflammatory signaling, linking innate immune detection to adaptive immune responses. T... ...