Brain voltage-gated Ca2+ channels and calmodulin: Teaming up in calmodulinopathies?
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Calmodulin (CaM) serves as one of the key cellular Ca2+ sensors with >300 targets and a highly conserved structure since its appearance in early eukaryogenesis. Three distinct CaM genes (CALM1, CALM2, and CALM3) encode one identical CaM protein in mammals. Thi... ...