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High-Dose methotrexate in pediatric acute lymphoblastic leukemia: Variability across Mexican centers from a national survey

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IntroductionHigh-dose methotrexate (HD-MTX) is a cornerstone of pediatric acute lymphoblastic leukemia (ALL) therapy. It's safe administration requires timely pharmacokinetic monitoring and comprehensive supportive care, which are frequently limited in low- a... ...