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Hemispheric H3K27M-mutant diffuse glioma in an adult: a rare entity with ATRX loss and Oligodendroglioma-like features

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The H3K27M genetic alteration is frequent in diffuse midline gliomas but rare in hemispheric diffuse gliomas. We report a rare case of a hemispheric H3K27M-mutant high-grade glioma in a 21-year-old female who presented with a seizure. Brain MRI revealed a 4.2 ... ...