Concept of natural genome reconstruction. Part 4. Integration of extracellular double-stranded DNA fragments into the genome of hematopoietic stem cells and the formation of extrachromosomal intermediates
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To assess the possibility of integrating extracellular double-stranded DNA fragments into the recipient genome of hematopoietic stem cells, a complex substrate was constructed consisting of the entire M13F-AluI-M13R fragment and its two restrictive derivatives... ...
