Single-site amino acid residue mutation reshapes the characteristics of double bond positions for protostadienol-type triterpenols
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Protostadienol-type tetracyclic triterpenes, characterized by a rare chair-boat-chair (C-B-C) cyclized sterol-type backbone, serve as high-value pharmaceutical precursors due to their positionally isomeric double bonds. Plant derived-protostane triterpenoids h... ...