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A novel green QbD-optimized RP-HPLC bioanalytical method for the simultaneous determination of doxorubicin and rifampicin in human plasma

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Doxorubicin hydrochloride (DOX) remains a cornerstone in the treatment of numerous malignancies. Recent research has focused on improving the efficacy of chemotherapeutic regimens through synergistic combinations. Rifampicin (RFP), in addition to its well-know... ...