Ultrafine particles induce ferroptosis-like stress features in human dopaminergic LUHMES cells via the p53/xCT/GSH/cGPx4 axis
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Parkinson's disease (PD) involves progressive loss of dopaminergic neurons in the Substantia Nigra pars compacta, with regulated cell death (RCD) pathways - ferroptosis and apoptosis - contributing to neurodegeneration. Ferroptosis, an iron-dependent form of ... ...
