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Roles of acidic residues in SpeG acetyltransferases-insights into importance for kinetic activity and polyamine binding in allosteric and acceptor sites

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The Gcn5-related N-acetyltransferases (GNATs) belong to a massive superfamily of enzymes that perform a wide array of functions in different organisms. This family is comprised of smaller subfamilies, including one called the spermidine/spermine N-acetyltransf... ...