Structural bioinformatics-based targeting of Epstein-Barr virus BPLF1 deubiquitinase activity against EBV infection and in-vitro validation
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We screened an in-house library of ~ 900 natural and naturally derived compounds to identify potential inhibitors targeting the BPLF1 deubiquitinase of Epstein-Barr virus, a significant regulator of the NF-κB signaling pathway and viral DNA replication. The v... ...
