Huntington's Disease Human Lateral Ganglionic Eminence Precursors Differentiate into Functionally Mature Medium Spiny Neurons Exhibiting Pathology
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Huntington's disease (HD) is an autosomal dominant neurodegenerative disease characterised by the loss of GABAergic medium spiny neurons (MSNs). Cellular models of HD are mainly derived from human embryonic stem cells or induced pluripotent stem cells. These ... ...