POU5F1/OCT4 Attenuates Human LINE-1 Expression Levels in Induced Pluripotent Stem Cells
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Long interspersed nuclear element-1 (LINE-1, L1) shows high transcriptional activity in human pluripotent stem cells (PSCs). Here, we showed that pluripotency-associated transcription factors (TFs) such as POU5F1 (OCT4), SOX2, KLF4, NANOG, and MYC bind to the ... ...
