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Leptomeningeal metastatic disease responding to carboplatin, pemetrexed, and amivantamab after progression to osimertinib in EGFR exon 21 L858R-Mutated non-small cell lung cancer: Two case reports

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Leptomeningeal metastatic disease (LMD) is associated with a poor prognosis in patients with epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) who experience disease progression after EGFR tyrosine kinase inhibitor therapy. Ami... ...