Compounds mimicking the Michaelis-Menten transition state of the phosphatidylinositol 4-kinase
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Phosphatidylinositol 4-kinases (PI4Ks) are crucial enzymes in lipid signaling responsible for generating phosphatidylinositol-4-phosphate (PI4P). Although the ATP-binding site of PI4Ks has been extensively studied, the structural characterization of their natu... ...
