Structure-based E-pharmacophore guided in silico repurposing of clinically approved drugs targeting methionyl-tRNA synthetase against leishmaniasis
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Leishmaniasis is a neglected tropical disease caused by Leishmania parasites and is associated with more than 1.3 million cases annually. The current therapeutic options include pentavalent antimonials, miltefosine, and amphotericin B, but their use is limited... ...
