Integrated Transcriptomic, Proteomic, and Pharmacologic Profiling of 2D and 3D Patient-Derived GCTB Cell Lines Reveals Culture-Dependent Drug Response Determinants
{{output}}
Giant cell tumor of bone (GCTB) is an intermediate bone neoplasm defined by recurrent H3F3A mutations and limited systemic treatment options beyond denosumab. Patient-derived cancer cell lines (PDCs) offer a scalable platform for mechanistic studies and therap... ...
