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Zinc-mediated structural and functional regulation of ERp44 and ERGIC-53 in protein quality control

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Zinc ions (Zn2+) are essential trace metal ions in the human body. Intracellular Zn2+ levels are tightly regulated by two metal transporter families: ZIPs, which mediate Zn2+ influx into the cytosol, and ZnTs, which export Zn2+ from the cytosol to the extracel... ...