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Comparison of Outcome Between Neoadjuvant Chemotherapy with Limb Salvage Surgery and Amputation with Chemotherapy in Osteosarcoma Patients: A Systematic Review

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Introduction: Osteosarcoma is a rare malignant bone tumour arising from primitive mesenchymal tissue, most often affecting males aged 10-30. Historically, treatment involved amputation or disarticulation, with a 5-year overall su... ...