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Design and synthesis of [1,2,4]triazolo[3,4-b]thiadiazine-1,2,4-oxadiazoles as EGFR tyrosine kinase inhibitors

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A novel series of heterocyclic compounds was developed, synthesized, and assessed for their in vitro anticancer efficacy and EGFR inhibitory activities. The cytotoxicity of the synthesized compounds was evaluated against A-549 and NCI-H460 lung cancer cell lin... ...